After graduation from Tufts Isaac produced international documentary films for the United Nations Children's Fund (UNICEF). He worked alongside Swaziland journalist James Tjekisa Hall and produced and directed three documentaries that explore the daily reality of HIV and AIDS and AIDS orphans. Isaac also produced numerous video projects and news segments for national broadcast on Swazi Television. His documentaries are distributed in over 27 countries and are helping promote awareness of AIDS in Africa and UNICEF's campaign to help orphans and vulnerable children.
Isaac traces his childhood roots from Iowa to Nigeria, Turkey, Pakistan, and China. He spent thirteen years moving around as a child and draws on the unique experience and perspective of an American outsider living overseas to inform his work.